We are currently recruiting for:
A competitively-funded PhD position:
A drug-resistance map for Leishmania populations in Brazil.
Apply here. Available for UK student only.
Application deadline: April 04, 2021
Background: Visceral leishmaniasis (VL) is a neglected disease caused by Leishmania infantum or L. donovani. More than 40,000 VL cases were reported in Brazil between 2008-2018, causing thousands of fatalities. This PhD project will study drug resistance in Leishmania infantum, which causes VL in Brazil.
The project will: use laboratory assays, genome sequencing technology and quantitative genetics to estimate the genetic contributions of drug resistance in L. infantum isolates from Brazil. With collaborators at York and Brazil, you will develop high-throughput methods to measure drug tolerance and cell fitness in Leishmania isolates. Using population genomics data from L. infantum strains from throughout Brazil, you will create a drug-resistance map that will have predictive power to monitor the spread of drug-resistance in South America.
Position starts: 1 October 2021.
Funding notes: This position is competitively funded from the James Burgess Scholarship fund. A number of projects are competing for this funding scheme, each will nominate their strongest candidate to a Selection Panel. Nominated candidates will be invited for interview but only one student will be offered the studentship.